Initiation of parturition
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From 105 days |
Foetal maturation of brain - hypothalmus |
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Stimulates foetal pituitary- produces ACTH |
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Stimulates foetal adrenal glands – produce corticosteroids |
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Placental progesterone to oestrogens |
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Increases myometrium sensity to oxytocin |
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Stimulates and softens cervix |
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Release of prostaglandins from uterus |
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Stimulates relaxin release which relaxes and softens cervix, pelvic ligaments and perineum |
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Increased myometrium sensitivity to oxytocin |
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Luteolysis of the corpus luteum which decreases progesterone |
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Myometrial activity increases |
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Vaginal/cervical stimulation
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Oxytocin release From pituitary |
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